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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSF
All Species:
22.73
Human Site:
Y724
Identified Species:
35.71
UniProt:
P46459
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46459
NP_006169.2
744
82594
Y724
S
L
Q
M
D
P
E
Y
R
V
R
K
F
L
A
Chimpanzee
Pan troglodytes
XP_511626
842
92301
Y797
S
L
Q
M
D
P
E
Y
R
V
R
K
F
L
A
Rhesus Macaque
Macaca mulatta
XP_001105450
854
93325
Y834
S
L
Q
M
D
P
E
Y
R
V
R
K
F
L
A
Dog
Lupus familis
XP_548044
752
83541
Y724
S
L
Q
M
D
P
E
Y
R
V
R
K
F
L
A
Cat
Felis silvestris
Mouse
Mus musculus
P46460
744
82595
Y724
S
L
Q
M
D
P
E
Y
R
V
R
K
F
L
A
Rat
Rattus norvegicus
Q9QUL6
744
82634
Y724
S
L
Q
M
D
P
E
Y
R
V
R
K
F
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418094
740
82158
L718
L
M
L
I
E
M
S
L
Q
M
D
P
E
Y
R
Frog
Xenopus laevis
P23787
805
89193
I752
R
S
V
S
D
N
D
I
R
K
Y
E
M
F
A
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
I752
R
S
V
S
D
N
D
I
R
K
Y
E
M
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46461
745
82537
Q724
A
R
Q
T
E
Q
S
Q
R
A
I
K
F
L
S
Honey Bee
Apis mellifera
XP_001120201
743
82591
R721
L
C
L
I
D
M
V
R
Q
V
E
P
S
Y
R
Nematode Worm
Caenorhab. elegans
Q94392
824
91316
A804
E
S
A
R
Q
C
E
A
D
Y
R
V
P
T
L
Sea Urchin
Strong. purpuratus
NP_999752
746
82671
V721
L
L
V
L
L
E
M
V
R
Q
T
E
P
S
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M0Y8
742
81469
G713
A
A
Q
G
E
N
G
G
S
A
E
A
I
Y
A
Baker's Yeast
Sacchar. cerevisiae
P18759
758
84038
E738
K
K
T
L
T
N
I
E
T
A
R
H
D
E
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
86.8
98.1
N.A.
98.1
97.8
N.A.
N.A.
93.6
26.2
25
N.A.
62.4
65.8
50.6
64.8
Protein Similarity:
100
88.2
87.1
98.8
N.A.
99.7
99.7
N.A.
N.A.
96.5
44.2
44.4
N.A.
77.7
81.1
66.2
80.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
20
20
N.A.
33.3
13.3
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
33.3
33.3
33.3
N.A.
53.3
26.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.5
44.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.6
64.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
7
0
0
0
0
7
0
20
0
7
0
0
60
% A
% Cys:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
60
0
14
0
7
0
7
0
7
0
7
% D
% Glu:
7
0
0
0
20
7
47
7
0
0
14
20
7
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
47
14
0
% F
% Gly:
0
0
0
7
0
0
7
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
14
0
0
7
14
0
0
7
0
7
0
0
% I
% Lys:
7
7
0
0
0
0
0
0
0
14
0
47
0
0
0
% K
% Leu:
20
47
14
14
7
0
0
7
0
0
0
0
0
47
7
% L
% Met:
0
7
0
40
0
14
7
0
0
7
0
0
14
0
0
% M
% Asn:
0
0
0
0
0
27
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
40
0
0
0
0
0
14
14
0
0
% P
% Gln:
0
0
54
0
7
7
0
7
14
7
0
0
0
0
0
% Q
% Arg:
14
7
0
7
0
0
0
7
67
0
54
0
0
0
14
% R
% Ser:
40
20
0
14
0
0
14
0
7
0
0
0
7
7
7
% S
% Thr:
0
0
7
7
7
0
0
0
7
0
7
0
0
7
0
% T
% Val:
0
0
20
0
0
0
7
7
0
47
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
40
0
7
14
0
0
20
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _